The Impact of Prednisone on Semen Parameters and Pregnancy Rates Post Vasectomy Reversal
Launched by CHARITABLE UNION FOR THE RESEARCH AND EDUCATION OF PEYRONIE'S DISEASE · Mar 6, 2021
Trial Information
Current as of May 27, 2025
Active, not recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how a medication called prednisone affects men who are having a vasectomy reversal, a procedure to restore fertility after a man has had a vasectomy. The researchers want to see if taking prednisone can improve sperm quality and increase the chances of pregnancy for the couple after the reversal. They will look at these effects in different groups of men taking prednisone and also check for any side effects related to its use.
To participate in this study, men must be between 18 and 65 years old and planning to have their first vasectomy reversal at a specific clinic. They also need to have a partner who is under 36 years old and does not have any known fertility issues. The couple should be eager to achieve pregnancy right away. However, certain medical conditions or past treatments may exclude some men from joining the study, such as previous vasectomy reversals or certain health problems. While the trial is currently active, it is not recruiting new participants at this time.
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • Men undergoing a first-time vasectomy reversal at the Male Fertility and Peyronie's Clinic
- • 18-65 years of age
- • Current sexual partner with desire to achieve pregnancy immediately
- • Intent of reversal to restore fertility
- • Partner \<36 years of age
- • Partner with no known fertility issues
- • Prior history of paternity
- Exclusion Criteria:
- • Current corticosteroid use
- • Prior vasectomy reversal
- • Prior chemotherapy
- • Testosterone use within 1 year of the vasectomy reversal
- • Solitary testicle
- • History of diabetes mellitus
- • History of systemic fungal infection
- • Hypertension
- • Any degree of diagnosed renal insufficiency
- • Partner on birth control within past 3 months
About Charitable Union For The Research And Education Of Peyronie's Disease
The Charitable Union for the Research and Education of Peyronie's Disease is a dedicated nonprofit organization committed to advancing the understanding and treatment of Peyronie's disease through rigorous clinical research and educational initiatives. This sponsor aims to improve patient outcomes by fostering collaboration among researchers, clinicians, and patients, while also raising awareness about the condition. By funding innovative studies and disseminating vital information, the union strives to enhance the quality of care and support available to individuals affected by Peyronie's disease.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Orem, Utah, United States
Patients applied
Trial Officials
Benjamin Green
Study Director
The Male Fertility and Peyronie's Clinic
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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