Cognitive Training and Brain Stimulation in Women With Post-chemotherapy Cognitive Impairment

Launched by UNIVERSITY MEDICINE GREIFSWALD · Mar 24, 2021

Keywords

ClinConnect Summary

This clinical trial is exploring whether a special type of brain stimulation, called high definition transcranial direct current stimulation (tDCS), combined with intensive memory training can help improve thinking skills in women who have experienced cognitive problems after chemotherapy for breast cancer. The study aims to find out if this approach can enhance memory and overall cognitive functioning in these individuals.

To participate in the trial, women aged 18 to 60 who have completed chemotherapy for breast cancer at least six months ago and feel that their thinking abilities have declined may be eligible. However, those with a history of dementia, certain neurological disorders, severe medical conditions, or specific psychiatric issues will not qualify. Participants can expect to engage in cognitive training sessions and receive brain stimulation to see if it helps improve their memory and thinking abilities. The study is currently recruiting participants, so it’s a great opportunity for eligible women seeking support for their cognitive health after cancer treatment.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Chemotherapy to treat breast cancer (≥ 6 months post-treatment).
• • 2. Self-reported concerns regarding cognitive functioning.
• • 3. Age: 18-65 years.
• • 4. right-handedness
• Exclusion Criteria:
• • 1. History of dementia before treatment of cancer.
• • 2. Other neurodegenerative neurological disorders; epilepsy or history of seizures.
• • 3. Severe and untreated medical conditions that preclude participation in the training, as determined by responsible physician.
• • 4. History of moderate to severe substance use disorder according to DSM-5
• • 5. Moderate to severe acute psychiatric disorders according to DSM-5
• • 6. Contraindication to tDCS application (Antal et al., 2017)