A Sibling Oocyte Study- Comparison of ZyMotTM Microfluidics Device to Density Gradient for Sperm Selection During ICSI

Launched by NYU LANGONE HEALTH · Mar 25, 2021

Keywords

ClinConnect Summary

During an in vitro fertilization (IVF) cycle, eggs are removed from a woman's ovaries via a minor surgical procedure and are inseminated with sperm in order to create embryos. The insemination process can be via standard IVF or intracytoplasmic sperm injection (ICSI.) Standard IVF is the process of placing thousands of sperm in a culture dish with one or more eggs and allowing them to interact on their own. ICSI is the process by which one sperm is directly injected into each egg.

Prior to using the sperm for insemination, a semen sample is processed and washed in order to obtain the healt...

Gender

ALL

Eligibility criteria

• Inclusion Criteria for Patients:
• • 1. Patient(s) over 18 years of age
• • 2. Patient(s) capable of providing informed consent
• • 3. Use or possible use of ICSI for oocyte insemination
• • 4. At least 6 mature oocytes at time of insemination via ICSI
• Exclusion Criteria for Patients:
• • 1. Patient under 18 y/o
• • 2. Patients not capable of providing informed consent
• • 3. Use of IVF for insemination
• • 4. Less than 6 mature oocytes at time of rertrieval
• • 5. Anonymous donor sperm source
• • 6. Surgically retrieved sperm
• • 7. Sperm sample not sufficient for use with ZyMot device
• Inclusion Criteria for Donors:
• • 1. Donor(s) over 18 years of age
• • 2. Donor(s) capable of providing informed consent
• • 3. Use of ejaculate sperm, fresh or frozen, for insemination
• • 4. Sufficient sperm for use of ZyMot
• Exclusion Criteria for Donors:
• • 1. Anonymous donors