The Use of Injectable Plasma Versus the Use of Simvastatin Gel in Surgical Management of Bony Defect in Dentistry

Launched by AIN SHAMS UNIVERSITY · Mar 30, 2021

Keywords

ClinConnect Summary

Group I ( Experimental group): will include 12 patients undergoing open flap debridement (OFD) followed by single application of I-PRF. Oral Hygiene measure will be instructed following treatment and maintenance visits will be given to them.

Group II (Control group): will include 12 patients undergoing open flap debridement (OFD) followed by application of 1.2% simvastatin gel. Oral Hygiene measure will be instructed following treatment and maintenance visits will be given to them.

* Oral hygiene instructions will be given to all patients.
* Full mouth Scaling and root planing (SRP) will ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • • Age range between 25 and 40 years
• • Patients with severe chronic periodontitis having probing depth (PD) ≥6 mm and clinical attachment loss (CAL) ≥5 mm , or Stage III periodontitis
• • Patient having vertical bone loss ≥3 mm (distance between alveolar crest and base of the defect as confirmed by preoperative intraoral periapical radiographs using standardized parallel technique.)
• • Good compliance with the plaque control instructions following initial therapy
• • Availability for follow up and maintenance program.
• Exclusion Criteria:
• • • Patient with any systemic disease or conditions
• • Patient using antibiotic, anti-inflammatory, and immunosuppressive therapy during the preceding 3 months before the start of trial and during the study.
• • Patients who have undergone any periodontal treatment in the last 6 months
• • Pregnant and Lactating.
• • Reported allergy to any type of statins
• • Subjects who were tobacco or alcohol users
• • Vulnerable group of patients (e.g.: prisoners , handicapped , or decisionally impaired individuals )