Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glaucoma or Ocular Hypertension: Clinical Effectiveness, Tolerability and Safety in a Real World Setting

Launched by SANTEN PHARMACEUTICAL (TAIWAN) CO., LTD · Mar 30, 2021

Keywords

ClinConnect Summary

The primary objective of this study is to assess the effectiveness of Tafluprost / Timolol in controlling ocular hypertension, as measured by mean change in intra-ocular pressure (IOP) from baseline to after 6 months of treatment from initiation, in patients with open angle glaucoma (OAG) or ocular hypertension (OHT), who do not respond sufficiently to initial topical treatment, in routine clinical practice.

This study will include adults with open angle glaucoma or ocular hypertension, who received their first Tafluprost / Timolol prescription at baseline, even if Tafluprost / Timolol was...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Signed informed consent obtained before any study-related activities (study-related activities are any procedure related to extraction of data according to the protocol)
• • According to the approved indications of Tafluprost / Timolol as indicated in the SPC
• • Male or female patients ≥20 years of age at time of informed consent
• • Diagnosis of open angle glaucoma or ocular hypertension
• • Insufficient IOP control with a monotherapy utilizing topical prostaglandin analogues, necessitating the use of a combination therapy according to the judgement of the treating ophthalmologist
• • Patient judged by their physician to benefit from preservative free eye drops
• • Not used Tafluprost / Timolol before
• Exclusion Criteria:
• • Patient pregnant or nursing
• • Pregnancy planned in the following 6 months
• • Presence of contraindications as listed in the SPC
• • Any ophthalmologic surgery within 6 months prior to the study
• • Participation in any other investigational study within 30 days prior to enrolment