THC + CBD and Memory Study

Launched by HARTFORD HOSPITAL · Apr 19, 2021

Keywords

ClinConnect Summary

The THC + CBD and Memory Study is designed to explore how using marijuana, specifically its active ingredients THC and CBD, affects memory. Researchers want to understand if CBD can help reduce memory problems caused by THC, the main psychoactive component of marijuana. To do this, they will use brain imaging (MRI) and various memory tests to assess how these substances impact thinking and memory skills.

The study is looking for right-handed individuals aged 65 to 74 who have used marijuana at least once in the past year but not more than once a month. Participants should be in good health and able to understand English well enough to follow the study instructions. It’s important to note that individuals who use certain medications, have a history of substance dependence, or have specific health conditions may not be eligible. If you join this study, you can expect to undergo memory testing and an MRI scan to help researchers learn more about how THC and CBD affect memory.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Right-handed
• • Prior MJ users (has used MJ at least once in the past year, but no more than 1x/month in the past 12 months)
• • Medically healthy (as determined by medical history and treatment)
• • Adequate comprehension of English in order to complete study materials
• • Acceptable birth control method for women (i.e., no copper IUD or any device that is not MRI safe)
• Exclusion Criteria:
• • Participant currently uses psychoactive medications or substances
• • Psychiatric diagnoses (determined by DSM-V)
• • Participant heavily or regularly uses MJ (more than 1x/month in the past year)
• • Current or past substance dependence (including MJ)
• • Positive urine toxicology screens
• • Positive pregnancy screens
• • MRI contraindications (e.g., heart pacemaker)