Assessment of TetraSOD® Efficacy to Improve Semen Parameters in Men With Idiopathic Infertility

Launched by FITOPLANCTON MARINO, S.L. · Apr 27, 2021

Keywords

ClinConnect Summary

IInfertility is an increasing global public health problem present in about 15-20% of the population of reproductive age, affecting as many as 186 million people worldwide. A male factor is present in approximately 50% of the infertile couples, a large number of them of unknown or idiopathic origin.

Spermatogenesis is a complex biological process that requires a highly regulated genetic and hormonal program in a singular environment created by the interaction with different cell types to orchestrate a successful differentiation process. This process occurs periodically every 72 days during...

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Age: 18 to 45
• • Male patients with idiopathic infertility classified with asthenozoospermia, oligozoospermia or oligoasthenozoospermia after seminal assessment.
• • Not achieving pregnancy after at least one year of intercourse with the same partner without protective measures
• Exclusion Criteria:
• • Azoospermia (absence of spermatozoa) or severe oligozoospermia (\< 5 million spermatozoa/ml of ejaculate)
• • Testicular torsion or prostatitis
• • Urinary retention and infections
• • Drug consumption
• • Hormone treatments
• • Recent surgical interventions
• • Diabetes
• • Kidney or liver disease
• • Leukocytosis
• • Antioxidant supplement consumption in the last 3 months
• • BMI \>30 Kg/m2
• • Endocrinopathies, hypo and hyperthyroidism
• • Chromosomal anomalies (XX, XYY, XXY)
• • Treatments with anticoagulants
• • Radiotherapy/Chemotherapy
• • Participation in another clinical study prior to inclusion in this study that could affect the objectives of the current study