Partial Pulpotomy in Mature Permanent Teeth With Signs and Symptoms of Irreversible Pulpits
Launched by NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS · Apr 28, 2021
Trial Information
Current as of May 22, 2025
Completed
Keywords
ClinConnect Summary
Study design This is a randomized controlled clinical superiority trial, parallel designed which will be conducted in compliance with the CONSORT and PRIRATE 2020 guidelines for reporting randomized trials in Endodontology recently published by the ESE (Nagendrababu et al. 2020a, b). During the study, two different bioactive materials will be tested upon their placement on exposed pulps of mature teeth with preoperative signs and symptoms indicating the presence of irreversible pulpitis. Patients referred to the Postgraduate Clinic of Endodontology of Dental School of National and Kapodistr...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients older than 10 years old.
- • Written consent after their update regarding the study and its aims.
- • Noncontributory medical history.
- • Extremely deep caries extending to the pulp chamber.
- • Positive response to cold sensibility testing.
- • Presence of spontaneous pain or provoked lingering pain to cold stimuli.
- • No clinical signs of pulp necrosis such as swelling or presence of a sinus tract.
- • Restorable and periodontally sound teeth.
- Exclusion Criteria:
- • Immature teeth.
- • Cariously involved teeth with no response to pulp sensibility tests.
- • No signs and symptoms of irreversible pulpitis.
- • Bleeding not controlled in 10 minutes after partial pulpotomy.
- • Teeth with no evidence of bleeding after communication with the pulp chamber (necrosis of the coronal pulp tissue)
- • Teeth with the pulp chamber exposed to the oral environment.
- • Detection of periodontal pocket with depth greater than 4mm.
- • Teeth suspected for crack or incomplete crown fracture possibly responsible for pulp pathology.
- • Medically compromised patients.
About National And Kapodistrian University Of Athens
The National and Kapodistrian University of Athens is a prestigious academic institution in Greece, renowned for its commitment to advancing medical research and education. With a strong emphasis on interdisciplinary collaboration, the university fosters innovative clinical trials aimed at improving healthcare outcomes. Its dedicated research teams leverage cutting-edge methodologies and a diverse range of expertise to address critical health challenges. As a clinical trial sponsor, the university prioritizes ethical standards and the welfare of participants, contributing significantly to the global body of medical knowledge and the development of new therapeutic interventions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Giorgos N Tzanetakis
Principal Investigator
Department of Endodontics, School of Dentistry, National and Kapodistrian University of Athens
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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