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Search / Trial NCT04915976

TAVI and Gender Outcomes Aortic Stenosis Undergoing Transfemoral Transcatheter Aortic Valve Implantation.

Launched by IMPERIAL COLLEGE HEALTHCARE NHS TRUST · Jun 1, 2021

Trial Information

Current as of June 12, 2025

Suspended

Keywords

Aortic Stenosis, Tavr, Tavi, Transcatheter Aortic Valve Implantation, Gender Differences

ClinConnect Summary

Severe aortic stenosis (AS) is the commonest form of valvular abnormality in the developed world and accounts for more than 40% of patients with native valvular disease with an approximately equal prevalence in males and females.

Transcatheter aortic valve implantation (TAVI) is now widely practiced with treatment of over 300,000 patients worldwide. Many centres now regularly implant devices in patients for whom conventional aortic valve replacement (AVR) is deemed high or intermediate risk. Several studies have shown that females have an apparent better outcome with TAVI than males.

Ther...

Gender

ALL

Eligibility criteria

  • All comers - retrospective registry

About Imperial College Healthcare Nhs Trust

Imperial College Healthcare NHS Trust is a leading healthcare provider in London, renowned for its commitment to delivering high-quality patient care and advancing medical research. As an integral part of the NHS, the Trust encompasses a range of specialized services and facilities, including multiple hospitals and outpatient centers, where it fosters a collaborative environment for clinical trials. With a focus on innovation and excellence, Imperial College Healthcare NHS Trust supports a diverse portfolio of clinical research initiatives aimed at translating scientific discoveries into effective treatments and improving health outcomes for patients. Its partnership with Imperial College London enhances its capabilities in cutting-edge research, making it a pivotal institution in the landscape of healthcare and clinical trials.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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