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Search / Trial NCT04946851

Addictions Neuroclinical Assessment (ANA)

Launched by NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (NIAAA) · Jun 30, 2021

Trial Information

Current as of May 29, 2025

Enrolling by invitation

Keywords

Executive Function Incentive Salience Negative Emotionality Neurobiology Alcohol Use Disorder Natural History

ClinConnect Summary

Study Description:

This is a protocol examining a battery of assessments designed to study three neurofunctional domains relevant to alcohol use disorder (AUD), negative emotionality, incentive salience and executive function. The study will examine the relationships among the three ANA domains with the goal of identifying sub-types of AUD based on variation in the ANA domains.

Objectives:

Primary Objectives:

1. To examine the relationship between the three ANA domains

(i.e. Negative Emotionality, Incentive Salience, Executive Function).
2. To identify the different subtypes of AUD ...

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • In order to be eligible to participate in this study, an individual must meet both of the following criteria:
  • 1. Participants must be \> 18 years of age
  • 2. Participants must have enrolled in the NIAAA Screening Protocol (14-AA-0181).
  • EXCLUSION CRITERIA:
  • There are no formal exclusionary criteria for this study. Based on enrollment criteria for the NIAAA Screening Protocol, individuals less than 18 years of age, or prisoners will not be enrolled in this study.
  • Outpatients will be tested for acute intoxication/impairment at the time of consent and study procedures using an alcohol breathalyzer and a clinical evaluation. Individuals with a positive breath alcohol concentration (BrAC), or those who are determined to be acutely intoxicated or impaired by the clinicians will be re-scheduled or withdrawn from the study.
  • In addition, individuals who are determined by the clinicians to be uncooperative or unable to provide consent, will not be invited to participate in this study. Individuals who report not being able to use a mouse and keyboard, or who are determined by the clinical research team to be unable to use a mouse and keyboard, will not be invited to participate in this study.

About National Institute On Alcohol Abuse And Alcoholism (Niaaa)

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is a leading federal agency dedicated to advancing research on alcohol-related health issues and fostering a deeper understanding of alcohol use disorders. As part of the National Institutes of Health (NIH), NIAAA supports a diverse portfolio of clinical trials aimed at developing innovative prevention and treatment strategies for alcohol abuse and dependence. By collaborating with researchers, healthcare providers, and community organizations, NIAAA strives to translate scientific findings into effective public health initiatives, ultimately aiming to reduce the impact of alcohol on individuals and society.

Locations

Bethesda, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Nancy Diazgranados, M.D.

Principal Investigator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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