Alternate Day Versus Daily Oral Iron Therapy in Adolescents

Launched by BAYLOR COLLEGE OF MEDICINE · Aug 16, 2021

Keywords

ClinConnect Summary

The research will be conducted at the following location(s):

Baylor College of Medicine, TCH: Texas Children's Hospital, and TCH: Texas Children's Hospital Clinic.

If patient appears to qualify for the study they will sign and date this consent form, and the doctor will confirm that they are eligible for the study. The patient will complete the following procedures:

* Medical history including prior hospitalizations, lab results, medications, diet, social and family history
* Physical Examination
* Blood samples: The patient will not have any extra blood draws (pokes) for this study. How...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 9 years or greater and less than age 22 years
• • 2. Heavy menstrual bleeding, defined as a Pictorial Blood Assessment Chart (PBAC) Score \>100
• • 3. Iron deficiency anemia, defined as both hemoglobin \<12 g/dL and ferritin \<15 ng/mL within 7 days of enrollment.
• Exclusion Criteria:
• • 1. non-uterine cause of vaginal bleeding
• • 2. pregnancy
• • 3. chronic kidney disease
• • 4. serology confirmed celiac disease
• • 5. active gastrointestinal blood loss
• • 6. active malignancy
• • 7. inability to follow-up at Texas Children's Hospital
• • 8. receipt of intravenous iron within 30 days prior to enrollment
• • 9. allergy or known inability to tolerate oral iron