Diazepam and Blood Pressure Regulation
Launched by UNIVERSITY OF BRASILIA · Sep 24, 2021
Trial Information
Current as of June 04, 2025
Completed
Keywords
ClinConnect Summary
Benzodiazepines are widely prescribed for a variety of clinical conditions. However, its cardiovascular consequences remain controversial. In this study, the investigators sought to determine the acute effects of a single dose of oral diazepam (10mg) on resting beat-to-beat blood pressure variability and cardiac and sympathetic baroreflex sensitivity in a cohort of young, healthy individuals.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 18 to 40 years of age
- • Healthy, free of known cardiovascular, metabolic, or musculoskeletal disease
- Exclusion Criteria:
- • History of smoking (tobacco or cannabis), defined as any smoking within the past 3 months
- • Diagnosed cardiovascular or metabolic disease(s)
- • Prescription of chronic medications other than oral contraceptives
- • History of hypertension or presence of arrhythmia
About University Of Brasilia
The University of Brasília is a prestigious academic institution dedicated to advancing medical research and education. As a clinical trial sponsor, it leverages its extensive resources and expertise to facilitate innovative research initiatives aimed at improving healthcare outcomes. The university fosters collaboration among leading researchers, healthcare professionals, and industry partners, ensuring the highest standards of ethical conduct and scientific rigor in its trials. With a commitment to addressing pressing health challenges and contributing to the global body of medical knowledge, the University of Brasília plays a pivotal role in the advancement of clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Brasília, Df, Brazil
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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