Combine Mirror Therapy and tDCS on CPSP
Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Nov 12, 2021
Trial Information
Current as of June 19, 2025
Completed
Keywords
ClinConnect Summary
Central poststroke pain (CPSP) refers to the symptom of pain arising after a stroke. Patients with CPSP often complain of various painful or unpleasant sensation.The feelings of pain may interfere with sleep and hugely affect the patients' quality of life. Additionally, CPSP may compromise rehabilitation and hinder movement recovery after stroke.
Non-invasive brain stimulation, such as repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS), is an emerging nonpharmacological treatment and has been shown to have promising pain reduction effects ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • (1) age ranges from 20 to 90 years old,
- • (2) history of unilateral ischemic or hemorrhagic stroke for more than 6 months,
- • (3) without severe weakness on affected side and able to catch things with affected hand,
- • (4) have neuropathic pain and/or sensory deficits occurring in the hemiplegic extremity (Visual Analog Scale ≥ 3), and
- • (5) do not have cognitive impairment (Mini-Mental State Examination ≥ 24).
- Exclusion Criteria:
- • (1) pain caused by reflex sympathetic dystrophy, peripheral neuropathy, structural lesions or due to psychological issues,
- • (2) a personal history of seizure or family history of epilepsy,
- • (3) metal implanted in the brain,
- • (4) implanted pacemaker,
- • (5) history of neurological or psychological diseases other than stroke,
- • (6) a history of head surgery or brain injury,
- • (7) unstable migraine or tinnitus that is not under medication control,
- • (8) aphasia,
- • (9) pregnancy or breastfeeding,
- • (10) poor response to present medication,
- • (11) under medication that may influence central nerve system (e.g. reducing threshold of seizure),
- • (12) skin sensitive to the application of electrical current,
- • (13) sleep deprivation, or
- • (14) severe or recent heart diseases.
About National Taiwan University Hospital
National Taiwan University Hospital (NTUH) is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a pioneer in medical education and patient care in Taiwan, NTUH integrates cutting-edge technology with comprehensive clinical expertise to facilitate groundbreaking studies across various medical fields. The hospital’s dedicated research team collaborates with local and international partners to enhance the understanding of diseases and improve treatment outcomes. By prioritizing patient safety and ethical standards, NTUH strives to contribute to the global medical community and foster advancements in healthcare practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Taipei, , Taiwan
Patients applied
Trial Officials
Sung-Chun Tang, PhD
Principal Investigator
National Taiwan University Hospital
Ya-Yun Lee, PhD
Principal Investigator
National Taiwan University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials