Interrupting HIV and TB Stigma in the Household in Uganda
Launched by YALE UNIVERSITY · Nov 5, 2021
Trial Information
Current as of June 22, 2025
Completed
Keywords
ClinConnect Summary
An estimated 39 million people worldwide are living with HIV, but nearly half do not know their status because they are unaware that they are at risk, unable to access counseling and testing, or unwilling to accept testing because of stigma and fear. Layered on to the stigma of HIV is the risk of tuberculosis (TB), the leading cause of death among persons living with HIV (PLWH). Home testing is a promising approach to increase testing and linkage to care for HIV because it can reach individuals outside the health system, eliminate the costs of traveling for testing, offer testing in a famil...
Gender
ALL
Eligibility criteria
- Index Patient and Household Eligibility:
- • Index patient is eligible for contact investigation (TB patient of any age identified in the facility's National TB and Leprosy Programme (NTLP) TB Treatment Register as initiating treatment or returning for 2-week follow-up)
- • Index patient or legal guardian agrees to study procedures in addition to routine contact investigation
- • Index patient has at least 2 self-reported household contacts age 15 or above
- • Household is within the boundaries of the Kampala Capital City Authority, Uganda
- • Does not have multi-drug resistant (MDR) TB
- Contact Participant Eligibility:
- • Household contact age ≥15 years
- • Agrees to study procedures in addition to routine contact investigation
About Yale University
Yale University, a prestigious Ivy League institution located in New Haven, Connecticut, is renowned for its commitment to advancing medical research and clinical innovation. With a rich history of academic excellence and a robust infrastructure for scientific inquiry, Yale serves as a leading sponsor for clinical trials aimed at improving patient care and developing new therapeutic approaches. The university's multidisciplinary teams of researchers and clinicians collaborate to conduct rigorous and ethical studies, leveraging cutting-edge technologies and methodologies to address critical health challenges. Through its dedication to fostering an environment of inquiry and discovery, Yale University plays a pivotal role in translating research findings into clinical practice, ultimately enhancing health outcomes for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kampala, , Uganda
Patients applied
Trial Officials
J. Lucian Davis, MD
Principal Investigator
Yale School of Public Health
Achilles Katamba, PhD
Principal Investigator
Makerere University
Mari Armstrong-Hough, PhD
Principal Investigator
New York University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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