Effect of Pre-emptive Intravenous Immunoglobulin (IVIG) on the Incidence of Septic Episodes in Pediatric Burn Patients

Launched by CAIRO UNIVERSITY · Nov 24, 2021

Keywords

ClinConnect Summary

After randomization, Treatment and control groups will receive Parkland formula (4 ml/kg per percent total burn surface area; (TBSA), counting moderate (partial thickness) and severe (full thickness) burn area only) using Ringer's lactate solution (half of the fluid will be given over the first eight hours and the remaining half will be given over the next 16 hours), plus normal 24-hour maintenance fluid requirements using glucose solution.

When initiating Parkland, treatment group (Group A) will receive intravenous immunoglobulin IVIG (LIV-GAMMA "S/D treated Human Immunoglobulin" 2.5 gram...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All burn patients 1 to 5 years old with 10% or greater burn area of TBSA .
• Exclusion Criteria:
• • Patients with septic shock (evidence of infection and inotropes) .
• • Burns more than 48 hours duration.