Effects of a Marine Protein Hydrolysate in Healthy Adults

Launched by UNIVERSITY OF BERGEN · Nov 25, 2021

Keywords

ClinConnect Summary

Marine protein sources, including fish and fish protein hydrolysates, may have particular health benefits. Health benefits from fish consumption have been attributed to the n-3 polyunsaturated fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Proteins from marine sources may contain valuable bioactive components, with amino acid composition and protein profiles that differ from terrestrial sources. Generally, the dietary source of protein can affect cellular energy metabolism, and hydrolyzed peptides can have potent and specific bioactive potential.

Res...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy female and male subjects at age 20-80 years old understanding Norwegian oral and written information
• • Waist circumference for males \< 102 cm and females \< 88 cm
• Exclusion Criteria:
• • Pregnancy or lactation
• • Having used high-dose omega-3 PUFA supplements (\>2 g/day) less than 28 days prior to randomization
• • Use of corticosteroids that will influence protein metabolism
• • Antibiotic treatment previous 3 months
• • Alcohol or drug abuse or any conditions associated with poor compliance
• • Medical diagnosis of malabsorption disorders, Crohn's disease, or lactose intolerance
• • Scheduled hospitalization during the course of the study that could compromise the study
• • Diabetes type I or II, serious high blood pressure at screening, serious infections, diseases requiring medication that can influence the study
• • Known or suspected sensitivity or allergic reactions to the IMP or excipients
• • Presence of other major medical or psychiatric illness that would affect the ability to participate in the study or put the subject at increased risk
• • Intake of statins. If needed to obtain the recruitment goals, we will accept people using a low dose of statin