Minimal Effective Concentration of Lidocaine in Propofol Lidocaine Mixture for Relief of Pain on Propofol Injection
Launched by IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY · Dec 9, 2021
Trial Information
Current as of June 06, 2025
Unknown status
Keywords
ClinConnect Summary
The research will be carried out in order to determine the optimal lidocaine concentration in propofol lidocaine mixture to prevent pain on propofol injection during induction of general anesthesia using a modified Dixon's up-and-down method. We hypothesized that focusing on lidocaine concentration and not dose could be more convenient and valuable to alleviate pain with propofol injection.
Patients \& methods include assessment of severity of pain on propofol injection using nine concentrations of lidocaine in in lidocaine propofol mixture in ASA I\&II patients aged 18-60 years with exclu...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • ASA I \&II
- • Age 18 - 60 years
- Exclusion Criteria:
- • study drug allergy
- • hepatic or renal impairment
- • cardiac problem
- • neurologic deficits
- • psychiatric disorders
About Imam Abdulrahman Bin Faisal University
Imam Abdulrahman Bin Faisal University (IAU) is a distinguished educational institution located in Saudi Arabia, dedicated to advancing healthcare through innovative research and clinical trials. With a commitment to excellence in medical education and community health, IAU actively engages in multidisciplinary studies that aim to enhance patient outcomes and contribute to evidence-based practices. The university's clinical trial initiatives are supported by a robust framework of ethical standards and regulatory compliance, ensuring the integrity and safety of its research endeavors. By fostering collaboration among researchers, healthcare professionals, and industry partners, IAU aims to drive significant advancements in medical science and improve the overall quality of healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Alaa Mohammed, MD
Study Director
King Fahd university hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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