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Search / Trial NCT05191966

Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy

Launched by ONDOKUZ MAYIS UNIVERSITY · Jan 13, 2022

Trial Information

Current as of April 26, 2025

Completed

Keywords

Regional Anesthesia Acute Pain Scores Subcostal Anterior Quadratus Lumborum Block Thoracic Paravertebral Block Morphine Consumption

ClinConnect Summary

Laparoscopic partial or radical nephrectomy is associated with severe acute postoperative pain. Acute pain is mediated by inflammation, activation of spinal pathways and muscle spasm. Poor pain control may reduce patient satisfaction, delay postoperative ambulation and increase the incidence of pulmonary and cardiac complications.

Facial plane blocks, an important element of multimodal analgesia, can reduce the dosage of opioids, minimize side effects and improve the quality of postoperative recovery. Quadratus lumborum (QL) block is a relatively new technique. Subcostal anterior QL block ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • ASA I-II patients aged 18-70 y, scheduled for elective laparoscopic unilateral nephrectomy(partial/radical)
  • Exclusion Criteria:
  • Age \<18y, \>70y
  • Obesity (BMI\> 30 kg / m2)
  • Pregnancy
  • Contraindication of regional anesthesia (coagulopathy, abnormal INR, thrombocytopenia, infection at the injection site)
  • Serious cardiac, hepatic, and cerebrovascular disease
  • Hypersensitivity to local anesthetics or a history of allergy
  • Patients with a history of opioid use longer than four weeks
  • Patients with psychiatric disorders or communication difficulties
  • Patients who do not want to participate
  • Asthma/chronic obstructive pulmonary disease, chronic pain syndrome, substance use disorder, or sleep apnea

About Ondokuz Mayıs University

Ondokuz Mayıs University is a prestigious academic institution located in Turkey, renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, the university leverages its cutting-edge facilities and a multidisciplinary team of experts to conduct innovative studies that aim to enhance patient care and contribute to scientific knowledge. With a focus on ethical standards and rigorous methodologies, Ondokuz Mayıs University is dedicated to fostering collaborations that drive breakthroughs in healthcare, ultimately improving treatment outcomes and patient well-being.

Locations

Samsun, Atakum, Turkey

Patients applied

0 patients applied

Trial Officials

Cengiz KAYA, MD

Study Director

Ondokuz Mayıs University Faculty of Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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