Comparison of Apexification and Regenerative Endodontic Therapy: a Retrospective Study
Launched by ISTANBUL UNIVERSITY · Jan 18, 2022
Trial Information
Current as of June 10, 2025
Completed
Keywords
ClinConnect Summary
The fractal dimension analysis of each radiograph was performed using the box-counting method proposed by White and Rudolph \[1\] (Figure 1). All periapical radiographs in high resolution Jpeg format to be included in the study was converted to tagged image file formats (TIFF). Each ROI at 18 x 19 pixels and 2 mm from the radiographic apex was selected, cropped and amplified. "Gaussian Blur" was used to eliminate the brightness changes due to soft tissues and variable bone thicknesses. The resulting image was then be subtracted from the original image. Bone marrow spaces and trabeculae were...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Apexification treatment was applied by a single operator (GK) in Istanbul University Faculty of Dentistry, Department of Pedodontics,
- • Having no systemic or periodontal problems,
- • Asymptomatic or diagnosed with apical periodontitis with fistula tract,
- • Not having external/internal resorption, fracture, more than one root/canal,
- • Root canal filling is sufficient for the MTA group,
- • Root canal filling and coronal restorations were completed in Istanbul University Faculty of Dentistry Department of Pedodontics,
- • Cases with periapical radiographs taken before the procedure and at least one year after the procedure was included.
- Exclusion Criteria:
- • Cases treated by different pediatric dentists,
- • Cases in which apexification is performed by different operators,
- • Cases with systemic or periodontal disease,
- • Cases with external/internal resorption, fracture, more than one root/canal,
- • Cases where root canal filling is not sufficient
- • Cases in which root canal filling and conoral restorations were completed over 2 years,
- • Cases without radiographs taken before or at least one year after the procedure,
- • Cases with artifacts in the periapical region on their radiographs
About Istanbul University
Istanbul University, a leading institution in Turkey, is dedicated to advancing healthcare through rigorous clinical research and education. Renowned for its commitment to scientific excellence and innovation, the university sponsors clinical trials that aim to enhance medical knowledge and improve patient outcomes. With a diverse team of researchers and healthcare professionals, Istanbul University fosters collaboration across disciplines to explore new therapeutic interventions and contribute to global health advancements. Its robust infrastructure and ethical standards ensure the highest quality in clinical trial management, making it a key player in the field of medical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Istanbul, , Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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