Human Milk-derived Fortification in Preterm Infants

Launched by UNIVERSITY OF CALGARY · Jan 26, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the effects of fortifying human milk for preterm infants who are born very small (weighing between 400 grams and 1250 grams). Since these tiny babies often struggle to get enough nutrition from human milk alone, the trial aims to see if adding special nutrients can help support their growth and health. The study will include infants who are born before 32 weeks of pregnancy and are expected to receive human milk for at least three weeks.

To participate in this trial, infants must meet certain conditions, such as being classified as appropriate for their gestational age and starting to receive human milk within 72 hours of birth. However, infants with serious health issues or certain maternal substance use during pregnancy will not be eligible. It's important to note that the trial is not yet recruiting participants, so families interested in this study will need to wait until it begins. The goal is to find better ways to help preterm infants grow and thrive during their crucial early weeks.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Birthweight between 400 g-1250 g
• • Less than or 32 weeks gestational age at birth
• • Subject has been classified as appropriate for gestational age
• • Enteral feeding of human milk is initiated by 72 hours
• • Subject is expected to be on human milk for at least 3 weeks.
• Exclusion Criteria:
• • Congenital abnormalities or underlying disease that may affect growth
• • Maternal cocaine, alcohol, or opioid abuse during pregnancy
• • Mother or infant is currently receiving treatment for HIV infection
• • Infant with major surgery