Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure
Launched by KAROLINSKA INSTITUTET · Feb 5, 2022
Trial Information
Current as of April 26, 2025
Unknown status
Keywords
ClinConnect Summary
OVERALL PURPOSE:
1. Study the underlying disease mechanisms in preeclampsia Investigate the physiological effects of dietary nitrate in preeclampsia, in order to increase the production of nitric oxide in the body.
SPECIFIC GOALS:
Can increased intake of nitrate via the diet:
* increase the availability and function of nitric oxide?
* improve vascular function?
* lower blood pressure?
* reduce the morbidity of these patients and their newborns?
BACKGROUND:
Preeclampsia (PE) is a multi-system disorder characterized by hypertension, proteinuria and intrauterine growth restriction, affec...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- Adult and decision-making patient who:
- • is pregnant from week 20
- • has normal blood pressure (controls) or high blood pressure during the current pregnancy (either chronic hypertension, gestational hypertension or preeclampsia)
- • are cared for at Danderyd Hospital (Women's Clinic; Obstetrics and Gynecology)
- Exclusion Criteria:
- • Type 1 diabetes
- • Vegetarians and vegans
- • Regular use/need for proton pump inhibitors (PPi)
- • Smoker
About Karolinska Institutet
Karolinska Institutet is a renowned medical university located in Sweden, recognized for its commitment to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the institution focuses on translating scientific discoveries into effective treatments and therapies, emphasizing patient-centered approaches. With a strong emphasis on collaboration and interdisciplinary research, Karolinska Institutet plays a pivotal role in addressing global health challenges and improving patient outcomes, leveraging its extensive network of experts and state-of-the-art facilities to drive clinical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Stockholm, , Sweden
Patients applied
Trial Officials
Mattias Carlstrom, PharmD, PhD
Principal Investigator
Karolinska Institutet
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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