Predictive Value of Sequential βHCG in IVF Pregnancy
Launched by ISTITUTO CLINICO HUMANITAS · Mar 22, 2022
Trial Information
Current as of April 29, 2025
Completed
Keywords
ClinConnect Summary
Fertility clinics follow different protocols for the measurement of βHCG. Typically the initial serum measurement is performed 10-12 days after blastocyst transfer or 12-14 days after transfer at cleavage stage. Often a second serum measurement of hCG is performed at 48h since an increase of at least 50% is known to be a good predictor of ongoing pregnancy.
The doubling time was first described in natural pregnancies where the rate of βHCG rise was reported to be at least 53% in two days, with a median of 50% increase at day 1 and 124% at day 2. Following the first detection and rise of se...
Gender
FEMALE
Eligibility criteria
- • All women that underwent IVF cycles (including fresh and thawed embryo transfers) between January 2011 and December 2020.
About Istituto Clinico Humanitas
Istituto Clinico Humanitas is a leading clinical research organization based in Italy, dedicated to advancing medical science through innovative clinical trials and research initiatives. With a strong emphasis on patient-centered care and cutting-edge methodologies, the institute collaborates with various stakeholders in the healthcare sector to develop and evaluate new therapies and treatment protocols. Its multidisciplinary team of experts is committed to ensuring the highest standards of ethical practice and scientific rigor, contributing to significant advancements in medical knowledge and improved patient outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Paolo Emanuele Levi Setti, MD
Study Director
Istituto Clinico Humanitas
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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