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Search / Trial NCT05333510

A Comparative Evaluation of TEG Versus ROTEM for Coagulopathy Correction

Launched by INSTITUTE OF LIVER AND BILIARY SCIENCES, INDIA · Apr 11, 2022

Trial Information

Current as of June 17, 2025

Completed

Keywords

Thromboelastography Thromboelastometry Nonvariceal Bleeding

ClinConnect Summary

Thromboelastography (TEG) and thromboelastometry( ROTEM) are point-of-care, global hemostasis assessment tests that measure the viscoelastic changes that occur during the hemostatic process.

Patients with cirrhosis have an imbalance of procoagulants and anticoagulants combined with alterations in fibrinolysis ,platelet number and function.

Point of care viscoelastic tests (TEG ,ROTEM) demonstrate specific functional coagulation defects that can direct blood component transfusion therapy in cirrhosis, with clinical validation of individual parameters.

Studies comparing Thromboelastography...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • patients of liver cirrhosis with non variceal bleed
  • Exclusion Criteria:
  • 1. Pregnant and postpartum patients
  • 2. died within the first 24hours of admission.
  • 3. variceal and postvariceal ligation ulcer bleed.
  • 4. On anticoagulants or antiplatelets at the time of admission in ICU
  • 5. Transfusion with blood products before admission to the ICU.

About Institute Of Liver And Biliary Sciences, India

The Institute of Liver and Biliary Sciences (ILBS) in India is a premier research and healthcare institution dedicated to the advancement of knowledge and treatment in liver, biliary, and related diseases. As a clinical trial sponsor, ILBS is committed to conducting innovative and ethically-driven research to improve patient outcomes and enhance therapeutic options in hepatology. The institute fosters collaboration among multidisciplinary teams of clinicians, researchers, and healthcare professionals, ensuring rigorous scientific methodologies and adherence to regulatory standards. Through its focus on translational research, ILBS aims to bridge the gap between laboratory discoveries and clinical applications, ultimately contributing to the global understanding and management of liver diseases.

Locations

New Delhi, Delhi, India

Patients applied

0 patients applied

Trial Officials

NIMI GOPAL

Principal Investigator

Institute of Liver and Biliary Sciences

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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