Validation of B-type Natriuretic Peptide With N-terminal Pro B-type Natriuretic Peptide in Perioperative Risk Assessment

Launched by JORDAN LEITCH · Apr 25, 2022

Keywords

ClinConnect Summary

This is a single-centre, prospective study to determine the correlation and comparative thresholds between NT ProBNP (Roche) and BNP (Abbott) tests. This will involve simultaneous serum sampling for both BNP and NT ProBNP at pre-surgical screening (PSS) or on the day of surgery (DOS). Serum sampling of BNP in this patient population is standard of care in our institution, thus only the additional blood required for the NT ProBNP test requires additional consent. Informed consent will be obtained at PSS or on the DOS by study staff. High sensitivity troponin I (Abbott) measurements will be t...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patient consents to study and is undergoing non-cardiac surgery and is one of:
• • Age \> 65 years
• • Revised cardiac risk index (RCRI) \>=1
• • Age \> 45 years old with significant cardiovascular disease (coronary artery disease, peripheral arterial disease, cerebral vascular disease, congestive heart failure, obstructive intracardiac disease such as severe aortic stenosis, severe mitral stenosis or severe hypertrophic obstructive cardiomyopathy)
• Exclusion Criteria:
• • Age \< 18 years
• • Patient undergoing cardiac surgery