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Search / Trial NCT05358015

Vascularized Bone Grafts for Treatment of Scaphoid Nonunion

Launched by ASSIUT UNIVERSITY · Apr 28, 2022

Trial Information

Current as of May 21, 2025

Unknown status

Keywords

ClinConnect Summary

The scaphoid is the most commonly fractured carpal bone accounting for 60% of fractures. A number of case series have identified a 10%-15% nonunion rate. Scaphoid nonunion refers to a spectrum of failed healing, each of which requires a tailored approach.

Subsequent to non-union, degenerative changes with the formation of cysts, bony resorption with loss of bone stock and the development of apex dorsal angulation or the humpback deformity may occur leading to scaphoid non-union advanced collapse (SNAC) of the wrist and the formation of a proximal pole which extends with the lunate.

This h...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All Patients will be included if they met the following criteria:
  • Age: all patient more than 18 years up to 55 years
  • Fracture: nonunion and a vascular necrosis proved by MRI (Herbert stage I or II) , humpback deformity, Proximal pole fracture, cystic degeneration, failed previous surgery (K wire, Herbert, plate distal radius)
  • Pain: persistent disabling pain and tenderness at wrist joint due to scaphoid nonunion.
  • patient: both sex will included, both handiness, good bone quality.
  • Exclusion Criteria:
  • Commuted Other carpus fractures
  • Nonunion less than 3 months
  • Radio-carpal Arthritis or instability

About Assiut University

Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.

Locations

Patients applied

0 patients applied

Trial Officials

Mohamed Kotb, M.D

Study Director

Assiut University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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