Comparison of Chemical Peeling Agent With Transamine for Treatment of Melasma
Launched by COMBINED MILITARY HOSPITAL ABBOTTABAD · Apr 30, 2022
Trial Information
Current as of May 23, 2025
Completed
Keywords
ClinConnect Summary
A randomized controlled trial study (single-blind) was done In the Dermatology Unit of the CMH, Abbottabad from June to November 2021 after Ethical Review Board approval, the 54 patients aged 20-50 years after informed consent were enrolled using a technique of non-probability consecutive sampling. The sample size was determined using the WHO sample size calculator, With a significance level of 95%, power of study 80%, the ratio of sample size B: A of 1 and Assumed MASI score in Group A (Tranexamic Acid) Mean + SD = 9.37 ± 2.18, in Group B (Glycolic Acid 70%) Mean + SD = 10.25 ± 2.93. Thus,...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients suffering from Melasma who attended the Dermatology department
- Exclusion Criteria:
- • history of hormone therapy and contraceptive pills (within the previous 12 months)
- • bleeding problems or concurrent use of anticoagulants
- • Topical treatment such as hydroquinone (one month prior to the research)
- • Active herpes simplex, face warts or active dermatoses
- • History of hypersensitivity to some of the study's components
- • Pregnant or lactating females
- • Patients with unrealistic expectations
About Combined Military Hospital Abbottabad
The Combined Military Hospital Abbottabad is a premier healthcare institution dedicated to providing high-quality medical services to military personnel and their families, as well as the local civilian population. As a clinical trial sponsor, the hospital leverages its advanced medical facilities and expertise in various healthcare disciplines to conduct innovative research aimed at improving patient outcomes and advancing medical knowledge. The institution is committed to upholding the highest ethical standards in clinical research, ensuring participant safety and compliance with regulatory guidelines while fostering collaboration with national and international research entities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Abbottābād, Kpk, Pakistan
Patients applied
Trial Officials
Naheed Khan
Principal Investigator
Cpsp
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials