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Search / Trial NCT05448586

Opioid Free Anaesthesia in Oncologic Gynaecological Surgery: Is There Any Benefit?

Launched by INSTITUTO DE INVESTIGACIÓN HOSPITAL UNIVERSITARIO LA PAZ · Jul 4, 2022

Trial Information

Current as of June 02, 2025

Completed

Keywords

Opioid Opioid Free Anesthesia Sirs (Systemic Inflammatory Response) Postoperative Infection

ClinConnect Summary

After Local Ethics Committee approval, consecutive consenting patients scheduled for major gynecologic oncologic surgery were included between February 2019 and January 2020 in this observational retrospective study. We Compared OFA to standard technique used in our institution and assessed its effect on Postoperative Systemic Inflammatory Response (SIRS), hospital stay, postoperative complications in the following 2 months, cancer progression and mortality 6 months and 12 months after surgery. OFA protocol consisted of a Total IntraVenous Anaesthesia of Propofol, a Dexmedetomidine infusion...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Patients who had Major Surgery for gynecologic cancers (cervix, endometrial, ovarian, vaginal, vulvar and breast cancer) under OFA and balanced anesthesia with opioids, both combined with regional anesthesia.
  • Exclusion Criteria:
  • Patients who had Major Surgery for gynecologic cancers (cervix, endometrial, ovarian, vaginal, vulvar and breast cancer) under OFA and balanced anesthesia with opioids, but had later surgery with a different to previous anesthesia technique.
  • Patients who had no later follow up during 12 months in the same Hospital, so we cannot register recurrence.

About Instituto De Investigación Hospital Universitario La Paz

Instituto de Investigación Hospital Universitario La Paz is a leading clinical research institution dedicated to advancing medical science and improving patient care through innovative research initiatives. Affiliated with one of Spain's premier hospitals, this institution fosters a collaborative environment that brings together healthcare professionals, researchers, and academics to conduct high-quality clinical trials across various therapeutic areas. With a commitment to ethical standards and patient safety, the institute aims to translate research findings into practical applications that enhance treatment outcomes and contribute to the global medical community.

Locations

Madrid, , Spain

Patients applied

0 patients applied

Trial Officials

Nicolas Brogly, PhD

Principal Investigator

Hospital Universitario La Paz

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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