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Search / Trial NCT05449925

Effect Of Injectable PRF And Microneedling In Patient Undergoing Orthodontic Treatment

Launched by POSTGRADUATE INSTITUTE OF DENTAL SCIENCES ROHTAK · Jul 7, 2022

Trial Information

Current as of May 24, 2025

Unknown status

Keywords

ClinConnect Summary

A non surgical, non invasive method of increasing gingival thickness has been reported using injectable platelet rich fibrin (i-PRF) alone and with microneedling (MN) in individuals with thin periodontal phenotype .

I-PRF is prepared as per low speed centrifugation concept that can provide a significant advantage for the regeneration process as it is rich in platelets, leukocytes, growth factors (As iprf is rich in WBC'c enabling slow and sustained release of growth factors as it clots and forms a gel approximately after 10-15 min and preserve its contents in the tissue for sustained relea...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • GT of the mandibular anterior teeth \<1mm (jepson et al. 2018) requiring labial orthodontic tooth movement without extraction.
  • Patients with \> 18 years who will be systemically healthy
  • full-mouth plaque index (PI) and full-mouth bleeding on probing (BOP) score of ≤ 15%
  • gingival index (GI) of \<1 (loe and silness) and dehiscence in mandibular anterior teeth detected in CBCT;
  • Exclusion Criteria:
  • Patients with thick gingival biotype (\>1mm gingival thickness as per Jepson et al.,2018) ;
  • Patient undergoing dental extraction for labial orthodontic tooth movement.
  • previous periodontal surgery;
  • systemic disease;
  • smokers
  • use of blood thinners;
  • use of any drugs that might lead to gingival enlargement;
  • mucogingival stress, bruxism.

About Postgraduate Institute Of Dental Sciences Rohtak

The Postgraduate Institute of Dental Sciences, Rohtak, is a premier academic institution dedicated to advancing dental education, research, and clinical practice. With a commitment to fostering innovation in oral health, the institute is actively engaged in conducting clinical trials that aim to enhance treatment methodologies and improve patient outcomes. By integrating cutting-edge research with comprehensive training, the institute plays a pivotal role in shaping the future of dental sciences, while adhering to the highest ethical standards and regulatory guidelines in clinical research.

Locations

Rohtak, Haryana, India

Patients applied

0 patients applied

Trial Officials

MRINALINI VERMA, BDS

Principal Investigator

PGIDS, ROHTAK

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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