Effect Of Injectable PRF And Microneedling In Patient Undergoing Orthodontic Treatment
Launched by POSTGRADUATE INSTITUTE OF DENTAL SCIENCES ROHTAK · Jul 7, 2022
Trial Information
Current as of May 24, 2025
Unknown status
Keywords
ClinConnect Summary
A non surgical, non invasive method of increasing gingival thickness has been reported using injectable platelet rich fibrin (i-PRF) alone and with microneedling (MN) in individuals with thin periodontal phenotype .
I-PRF is prepared as per low speed centrifugation concept that can provide a significant advantage for the regeneration process as it is rich in platelets, leukocytes, growth factors (As iprf is rich in WBC'c enabling slow and sustained release of growth factors as it clots and forms a gel approximately after 10-15 min and preserve its contents in the tissue for sustained relea...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • • GT of the mandibular anterior teeth \<1mm (jepson et al. 2018) requiring labial orthodontic tooth movement without extraction.
- • Patients with \> 18 years who will be systemically healthy
- • full-mouth plaque index (PI) and full-mouth bleeding on probing (BOP) score of ≤ 15%
- • gingival index (GI) of \<1 (loe and silness) and dehiscence in mandibular anterior teeth detected in CBCT;
- Exclusion Criteria:
- • Patients with thick gingival biotype (\>1mm gingival thickness as per Jepson et al.,2018) ;
- • Patient undergoing dental extraction for labial orthodontic tooth movement.
- • previous periodontal surgery;
- • systemic disease;
- • smokers
- • use of blood thinners;
- • use of any drugs that might lead to gingival enlargement;
- • mucogingival stress, bruxism.
About Postgraduate Institute Of Dental Sciences Rohtak
The Postgraduate Institute of Dental Sciences, Rohtak, is a premier academic institution dedicated to advancing dental education, research, and clinical practice. With a commitment to fostering innovation in oral health, the institute is actively engaged in conducting clinical trials that aim to enhance treatment methodologies and improve patient outcomes. By integrating cutting-edge research with comprehensive training, the institute plays a pivotal role in shaping the future of dental sciences, while adhering to the highest ethical standards and regulatory guidelines in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rohtak, Haryana, India
Patients applied
Trial Officials
MRINALINI VERMA, BDS
Principal Investigator
PGIDS, ROHTAK
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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