The Effect of Breast Milk Odor on Pain Response and Salivary Cortisol Level in Preterm Infants

Launched by TAIPEI MEDICAL UNIVERSITY · Sep 27, 2022

Keywords

ClinConnect Summary

Preterm infants need to undergo more invasive medical interventions than full-term healthy newborns to maintain their lives. Physiological functions changes brought about by pain and stress stimulations may complicate nerve development in preterm infants. Therefore, providing positive sensory supportive interventions to reduce pain and stress is imperative for preterm infants. Studies have confirmed that the use of painkillers, breastfeeding, swaddling, kangaroo care, giving glucose or sucrose can help reduce pain. The sense of smell matures at 28 weeks of gestation age, and newborns can re...

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Eligibility criteria

• Inclusion Criteria:
• • 1. Premature babies whose gestational age is between 30 weeks to 36 weeks and six days, with a birth weight \> 1000 grams.
• • 2. Apgar Score \> 6 at 5 minutes of birth.
• • 3. Within 10 days of birth, the vital signs are stable.
• • 4. Those who have medical needs, such as blood monitoring of neonatal serum bilirubin, blood sugar, electrolyte, or neonatal screening, etc., need heel puncture blood sampling.
• Exclusion Criteria:
• • 1. Those who have been diagnosed by a physician with severe congenital malformations, chromosomal abnormalities, respiratory distress, epilepsy, necrotizing enterocolitis, intracranial hemorrhage, periventricular leukomalacia, sepsis, meningitis, or hyperbilirubinemia.
• • 2. Those who have bronchopulmonary dysplasia or other chronic lung diseases that require the use of ventilator or non-invasive positive pressure respiratory support.
• • 3. Have used analgesics or anesthetics within 48 hours before giving the intervention of the study, or are participating in other studies that provide intervention for pain reduction.