Intrathecal Dexamethasone and Atropine on Morphine Induced Post-operative Nausea and Vomiting on Caesarean Section

Launched by ASSIUT UNIVERSITY · Sep 28, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how well intrathecal (IT) dexamethasone and atropine can help prevent nausea and vomiting caused by morphine after a cesarean section (C-section). Morphine is often used to manage pain after surgery, but it can lead to uncomfortable side effects like nausea and vomiting. The researchers want to see if giving these medications directly into the spinal area, along with morphine, can help reduce these side effects for women undergoing elective C-sections.

To participate in the trial, women aged 18 to 45 who are scheduled for an elective C-section under spinal anesthesia may be eligible. However, those with certain medical conditions, such as bleeding disorders or respiratory issues, and those who refuse to participate will not be included. If you join the study, you can expect to receive treatment during your surgery and will be monitored afterward to see how well the medications work in preventing nausea and vomiting. This research aims to improve the comfort and recovery of women after C-sections by addressing the side effects of pain relief medications.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Female
• • 2. 18-45 years old
• • 3. ASA: 1, 2
• • 4. Elective caesarean section under spinal anaesthesia.
• Exclusion Criteria:
• • 1. Patient refusal.
• • 2. Contraindications to spinal anaesthesia as coagulopathy, infection at site of injection, hemodynamic instability and uncooperative patient.
• • 3. Contraindications to administration of morphine as asthmatic patient and hypersensitivity and contraindications to any of the study drugs.
• • 4. Adult-Emergency CS as there is no time for preparation and risk on fetus and mother for time consuming