The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain.

Launched by DANISH HEADACHE CENTER · Sep 29, 2022

Keywords

ClinConnect Summary

This clinical trial is looking into how certain channels in the brain, called ATP-sensitive potassium (KATP) channels, might play a role in migraine headaches and the aura that some people experience before a migraine. Researchers want to find out if opening these channels leads to migraine pain and if it can trigger the changes in the brain that cause aura symptoms, such as visual disturbances.

To participate in this study, you need to be between 18 and 60 years old and have a history of migraines. You're eligible if you weigh between 50 and 100 kg and are generally healthy, without serious medical conditions or other types of headaches. Women who can become pregnant must use effective birth control during the study. If you join, you will help researchers understand more about migraines, and you may undergo some tests, including MRI scans, to gather important information. The trial is currently recruiting participants, so if you’re interested, it could be a great opportunity to contribute to migraine research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Migraine patients
• • 18-60 years.
• • 50-100 kg.
• • Women of childbearing potential must use adequate contraception.
• Exclusion Criteria:
• • A history of serious somatic disease
• • Any other type of headache (except episodic tension-type headache less than once a month) Daily intake of any medication except contraceptives Contraindications for MRI scan.