Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy

Launched by MONASH UNIVERSITY · Oct 15, 2022

Keywords

ClinConnect Summary

The STAREE-Mind imaging sub-study is looking at how a type of medication called statins, which are often used to lower cholesterol, might affect brain health in older adults over four years. The goal is to see if taking statins can help reduce signs of brain health issues, such as memory decline or other types of dementia. This study is currently active but not enrolling new participants.

To be eligible for the study, participants need to be at least 70 years old, living independently, and able to provide consent to join. They should also be part of a larger study (the STAREE RCT) and be willing to undergo brain imaging at one of the two study locations in Melbourne or Brisbane. Participants will have regular check-ins and brain scans to monitor their health over the study period. It's important to note that some people may not be able to join if they have had certain brain surgeries or have specific health issues that prevent them from having an MRI scan.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants in the STAREE RCT and eligible for randomisation to study medication.
• • Men and women
• • Aged ≥70 years
• • Living independently in the community
• • Willing and able to provide informed consent and agree to participate in brain neuroimaging.
• • Able to attend one of the 2 sites (in Melbourne and Brisbane) where the imaging will take place.
• Exclusion Criteria:
• • Contraindications to have magnetic resonance neuroimaging performed.
• • History of invasive brain surgery or known structural bran abnormalities.