Efficacy of PLDD Versus ESI in the Treatment of Lumbar Radicular Pain

Launched by OSIJEK UNIVERSITY HOSPITAL · Oct 26, 2022

Keywords

ClinConnect Summary

The hypothesis is that:

* there will be no difference in effectiveness in reducing the intensity of pain, improving the quality of life, reducing the degree of disability, reducing neuropathic pain, reducing anxiety and depression, and improving the quality of sleep in the treatment of lumbar radicular pain caused by disc herniation without discoradicular contact, but PLDD will be more effective in patients where there is discorradicular contact
* PLDD will lead to a greater reduction in serum levels of inflammatory markers in patients with nerve compression by intervertebral disc herniati...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 18 and 60
• • Signing informed consent
• • Unilateral lumbar radicular pain
• • Subjects who do not responds to conservative treatment
• • Disc herniation at one level
• • MR verified disc herniation
• • Pain intensity measured by VAS scale, from 0 - 10, \>5
• Exclusion Criteria:
• • Subjects younger than 18 and older than 65 years
• • Refusal of the subjects to participate in the research
• • Central stenosis of the lumbar canal
• • Lumbar radicular pain caused by causes other than intervertebral disc herniation
• • Pregnancy
• • Allergy to steroids, local anesthetics, fentanyl, midazolam and contrast medium
• • Positive history of prolonged bleeding
• • Local or systemic infection
• • Previous lumbar spine surgery7
• • Opioid abuse
• • Proven inflammatory rheumatic disease and inflammatory bowel disease in the active phase
• • Other acute infections