Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye

Launched by PEKING UNIVERSITY THIRD HOSPITAL · Oct 30, 2022

Keywords

ClinConnect Summary

This clinical trial is studying patients with dry eyes caused by Primary Sjögren's syndrome, a long-lasting condition where the immune system mistakenly attacks the body's moisture-producing glands. The goal is to better understand how different forms of this condition affect dry eye symptoms and to find ways to help manage them. The study is currently recruiting participants aged between 65 to 74 years old, as well as those between 29 to 219 years old, regardless of gender.

To be eligible for the trial, participants must have been diagnosed with dry eye according to specific guidelines and meet the criteria for Primary Sjögren's syndrome. However, those with certain other health conditions, histories of eye surgery or trauma, contact lens use, or specific eye problems will not be able to join. Participants can expect to undergo various examinations and assessments related to their eye health. Additionally, this study aims to gather important data that could lead to better treatments for people suffering from dry eyes linked to this syndrome.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All enrolled DED participants met the criterion of TFOS DEWS II Definition and Classification Report and pSS-DED group also met 2016ACR/EULAR pSS diagnosis and classification consensus.
• Exclusion Criteria:
• • (1) patients were diagnosed as any rheumatic or systematic diseases that would probably affect tear function except for pSS and DED. (2) had a history of ocular trauma or surgery. (3) had a history of wearing contact lens. (4) had concomitant ocular lesions such as acute inflammation or infection, glaucoma or eyelid abnormalities. (5) cannot cooperate properly or finish related examinations.