Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial

Launched by KHYBER MEDICAL UNIVERSITY PESHAWAR · Nov 8, 2022

Keywords

ClinConnect Summary

Historically, male infertility was considered a taboo subject and its role was deliberately kept in dark until recently when with advances in medical science, the issue was highlighted and its role came into limelight in couple's infertility. Male infertility is mainly caused by oxidative stress. O2- (superoxide anion), OH- (hydroxyl ions), H2O2 (hydrogen peroxide), nitric oxide \& ROO- (peroxyl) radicals are all oxygen derived highly reactive oxygen species with a free unpaired electron in their outer orbit making them short lived, highly reactive \& unstable. They are produced by the sper...

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Treatment naïve primary male infertile patients with Oligospermia, Asthenozoospermia , Teratozoospermia \& Necrozoospermia
• • 2. Aged between 20 - 45 years
• • 3. Married for more than a year with regular intercourse minimum 3/week.
• • 4. Normal female partner with normal menstrual cycle
• Exclusion Criteria:
• • 1. Azoospermic patients
• • 2. Patients with varicocoele
• • 3. Erectile dysfunction
• • 4. Secondary infertility
• • 5. Patients already taking treatment for primary infertility