CV Imaging of Metabolic Interventions

Launched by THE CLEVELAND CLINIC · Dec 5, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how certain medical treatments, like bariatric surgery (a weight loss surgery) and cardiac rehabilitation (a program to improve heart health), affect the heart's structure and function in people with heart failure and cardiovascular diseases. The researchers want to learn about changes in the heart's metabolism and health by using advanced imaging techniques called Magnetic Resonance Imaging (MRI) to get detailed pictures of the heart tissue. Understanding these changes is important for improving care and outcomes for patients with heart-related issues.

To participate in this study, you need to be at least 18 years old and give your consent to join. If you're in the bariatric surgery group, you should have obesity (a body mass index, or BMI, of 30 or higher) or be a healthy control (with a BMI below 30). If you're in the cardiac rehabilitation group, you should have symptoms of heart disease or be a healthy control with no heart issues. Participants will undergo imaging tests and possibly take part in treatment programs, helping researchers see how these interventions can improve heart health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \> 18 years of age
• • Provision of written informed consent
• • For bariatric surgery group, obesity (BMI\>/=30 kg/m2) and non-obese (BMI \<30 kg/m2; for control group)
• • For cardiac rehabilitation group, symptomatic cardiovascular disease for patients and no signs of cardiovascular disease for healthy controls
• Exclusion Criteria:
• • Vulnerable populations will be excluded from this study including Prisoners
• • Contraindication to CMR imaging to be determined by standard MRI protocols
• • Decisionally impaired (e.g. dementia or cognitive disability)