Effectiveness of Core Stabilization Exercises With and Without Neural Mobilization Technique in Female Patients With Lumbar Radiculopathy Due to Disc Herniation - an RCT Study
Launched by DOW UNIVERSITY OF HEALTH SCIENCES · Dec 15, 2022
Trial Information
Current as of June 17, 2025
Unknown status
Keywords
ClinConnect Summary
This clinical trial is studying how effective certain exercises are for women suffering from lower back pain caused by a lumbar disc herniation, which is when a disc in the lower spine slips out of place and can press on nearby nerves. The trial specifically looks at core stabilization exercises, which help strengthen the muscles around the spine, both with and without an additional technique called neural mobilization. Neural mobilization involves gentle movements to help improve the function of the nerves. The goal is to see if these exercises can reduce pain, improve movement, and enhance the quality of life for participants.
To be eligible for this study, participants must be women aged 30 to 50 who have been diagnosed with a lumbar disc herniation confirmed by an MRI, and have been experiencing pain radiating down one leg for more than three months. They should also have specific signs during a physical test that indicate nerve involvement. However, women with certain spinal conditions, severe vascular diseases, or other serious health issues will not be included. Participants can expect to engage in supervised exercise sessions and will be monitored throughout the study to assess their progress. This research aims to provide valuable insights into effective treatments for this common condition.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Diagnosed and referred females with lumbar disc herniation.
- • 2. Have a confirmed L4-S1 lumbar disc herniation through an MRI.
- • 3. Postero-lateral Disc herniation of stage I \& II.
- • 4. Age group of 30-50 years.
- • 5. Low back pain radiating to one leg for more than 3 months.
- • 6. Positive SLR test reproducing symptoms between 40°-70°.
- Exclusion Criteria:
- • 1. Spondylolisthesis, spondylitis, and spinal canal stenosis.
- • 2. Red flags: spinal tumors, cuada equina syndrome, spinal fractures, osteoporosis, infection.
- • 3. Severe vascular disease like DVT.
- • 4. Pregnancy and Gynecological problems.
- • 5. Psychological disorders affecting subject's ability to follow instructions.
About Dow University Of Health Sciences
Dow University of Health Sciences (DUHS) is a premier educational and research institution based in Karachi, Pakistan, dedicated to advancing healthcare through innovative research and clinical excellence. As a clinical trial sponsor, DUHS integrates cutting-edge scientific inquiry with practical applications, fostering a collaborative environment that promotes the development of new treatments and therapies. The institution is committed to upholding the highest ethical standards in research, ensuring participant safety, and contributing to the global body of medical knowledge. With a focus on interdisciplinary collaboration and community health impact, DUHS plays a pivotal role in enhancing the quality of healthcare both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Karachi, Sindh, Pakistan
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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