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Search / Trial NCT05672329

Functional Residual Capacity Under Apnoeic Oxygenation with Different Flow Rates in Children

Launched by THOMAS RIVA · Dec 21, 2022

Trial Information

Current as of May 05, 2025

Completed

Keywords

Atelectasis Apnoeic Oxygenation High Flow Nasal Oxygen Silent Spaces Functional Residual Capacity Paediatric Anaesthesia

ClinConnect Summary

High-flow nasal oxygen (HFNO) is the administration of heated, humidified and blended air/oxygen via nasal cannula at rates ≥ 2 L/kg/min. HFNO is an open system that can be used with nasal prongs of different sizes and was developed in neonatal intensive care unit for preterm babies with apnoea as alternative to continuous positive airway pressure (CPAP). Due to its ease of use and safety to apply to a wide range of indication HFNO is increasingly gaining interest for providing respiratory support in paediatric patients and in adults in ICU with respiratory failure. In adult populations, th...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Written informed consent by legal guardian
  • Paediatric patients undergoing elective surgery requiring general anaesthesia at the Bern University Hospital - Inselspital in Bern
  • Child weight between 10-20kg
  • American Society of Anesthesiology (ASA) physical status 1 \& 2 (healthy child, no severe co-morbidities)
  • Exclusion Criteria:
  • Known or suspected difficult intubation
  • Oxygen dependency
  • Congenital heart or lung disease
  • Obesity BMI (kg/m2) \>30
  • High aspiration risk (requiring rapid sequence intubation).

About Thomas Riva

Thomas Riva is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes. With a focus on innovative therapies and evidence-based practices, the organization collaborates with leading researchers and healthcare institutions to design and conduct rigorous clinical trials. Thomas Riva prioritizes ethical standards and patient safety, ensuring that all studies are conducted in compliance with regulatory guidelines. By fostering partnerships and leveraging cutting-edge technologies, Thomas Riva aims to accelerate the development of groundbreaking treatments that address unmet medical needs.

Locations

Bern, , Switzerland

Patients applied

0 patients applied

Trial Officials

Alexander Fuchs, M.D.

Principal Investigator

Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital,

Thomas Riva, M.D.

Study Director

Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital,

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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