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Search / Trial NCT05683782

Erythropoietin Gel as an Adjunct to Split-Thickness Apically Positioned Flap in Augmentation of Attached Gingiva

Launched by AIN SHAMS UNIVERSITY · Dec 27, 2022

Trial Information

Current as of May 14, 2025

Unknown status

Keywords

ClinConnect Summary

This clinical trial is investigating the use of a special gel called erythropoietin to help improve healing after a specific dental surgery designed to increase the width of attached gums. The goal is to see if applying this gel on the surgery site can help reduce discomfort after the procedure and improve patient satisfaction, while also increasing the amount of attached gum tissue.

To participate in the trial, you need to be between 20 and 40 years old, in good overall health, and meet certain dental conditions, such as having less than 2mm of attached gum tissue in the front of your lower teeth. Unfortunately, smokers, pregnant or breastfeeding women, and individuals with certain dental issues or health concerns cannot take part. If you join the study, you can expect to receive the erythropoietin gel during your treatment and will be asked to follow up to monitor your healing process. This research aims to find better ways to support recovery after dental surgeries.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Males and females within age range of 20-40 years.
  • Patients free of systemic diseases according to Burket's oral health history questionnaire .
  • Patients who can follow and maintain oral hygiene instructions.
  • Patients having insufficient width of attached gingiva (\<2mm) in labial aspect of lower anterior or premolar teeth and Miller Class I recession .
  • Thick gingival phenotype.
  • Exclusion Criteria:
  • Smokers.
  • Pregnant and lactating females
  • Unwillingness or inability to return for follow-up appointments
  • High frenum attachment
  • Crowding of test site teeth
  • Vulnerable patients (those with mental or physical impairments).

About Ain Shams University

Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Trial Officials

Ahmed E Amr, Assoc.Prof

Study Director

Ain Shams University

Hala k Abdelgaber, Professor

Study Director

Ain Shams University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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