Letrozole vs Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovarian Syndrome
Launched by SERVICES INSTITUTE OF MEDICAL SCIENCES, PAKISTAN · Jan 18, 2023
Trial Information
Current as of April 26, 2025
Completed
Keywords
ClinConnect Summary
The prevalence of infertility due to polycystic ovarian syndrome in Pakistan is 21.9%.It leads to an ovulation which results in infertility.The objective of this study was to compare the efficacy of letrozole vs clomiphene citrate for ovulation induction in PCOS women.Methods.It was a randomised controlled trial conducted in department of gynaecology and obstetrics ,Services Hospital Lahore from 2016-2019.
Total 230 patients were included in study, they were divided in two groups, out of which 220 patients were analysed. .Group-A patients were given clomiphene citrate 50-150mg per day for ...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women age between 18-40 years.
- • Normal husband semen analysis.
- Exclusion Criteria:
- • All infertile couples who had other causes of infertility than PCOS.
- • Those who had recently taken these medications.
- • Any contraindication to use of drugs e.g renal or hepatic dysfunction, hypersensitivity to this drug.
- • BMI\>35 because obese women respond poorly to ovulation induction.
About Services Institute Of Medical Sciences, Pakistan
The Services Institute of Medical Sciences (SIMS) in Pakistan is a prominent medical institution dedicated to advancing healthcare through rigorous research and clinical trials. With a mission to enhance medical knowledge and improve patient outcomes, SIMS engages in a wide range of clinical studies across various specialties. The institute is committed to adhering to international ethical standards and regulatory guidelines, ensuring the integrity and quality of its research endeavors. By fostering collaboration among healthcare professionals and academic researchers, SIMS aims to contribute significantly to the medical field and promote evidence-based practices in healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Lahore, Punjab, Pakistan
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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