Pain Informed Movement for People With Knee Osteoarthritis
Launched by MCMASTER UNIVERSITY · Feb 7, 2023
Trial Information
Current as of May 20, 2025
Completed
Keywords
ClinConnect Summary
This clinical trial, called "Pain Informed Movement for People With Knee Osteoarthritis," is exploring two different exercise programs to see which one helps people with knee osteoarthritis (OA) more effectively. One program focuses on understanding pain and includes education about pain science, while the other is a standard exercise program combined with general information about OA. The trial aims to find out if these programs can be easily managed, how satisfied participants are with each approach, and whether there are differences in pain levels, physical function, quality of life, and other health markers after participating.
To be eligible for this trial, participants need to be at least 40 years old and diagnosed with knee osteoarthritis or have knee pain linked to activity. They should experience mild pain on most days. However, people with certain conditions or recent surgeries, those who can't communicate in English, or those currently involved in other treatments for knee pain won’t be able to participate. If enrolled, individuals can expect to engage in one of the two exercise programs and answer questions about their pain and overall health throughout the study. This is an opportunity to contribute to research that could improve treatment options for knee osteoarthritis.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • - ≥40 years of age with diagnosis of knee osteoarthritis (OA) by a physician OR;
- • ≥45 years of age and having activity-related knee joint pain with or without morning stiffness lasting 30 minutes (NICE criteria)
- • Having an average pain intensity of 3/10 on a numeric pain scale on most days of the past month
- Exclusion Criteria:
- • Cannot communicate in English;
- • Has inflammatory arthritis or other systemic conditions;
- • Have had lower limb trauma or surgery within the past 6 months;
- • Have participated in a knee OA exercise program in the prior 3 months;
- • Have had any injection in the index knee within 3-months prior to baseline assessment
- • Does not have regular access to the internet
- • Inability to get up and down from the floor independently
- • Use of mobility aids
- • Currently participating in any other drug/device/exercise clinical trial related to OA
- • Planned absences (e.g., trips away) of \>1 week
- • Currently receiving other forms of care for knee OA pain (e.g., from a physiotherapist, chiropractor, athletic therapist, kinesiologist)
- • Does not meet screening for safe participation in exercise according to the Get Active questionnaire from the Canadian Society for Exercise Physiology
About Mcmaster University
McMaster University, a leading research institution located in Hamilton, Ontario, Canada, is renowned for its innovative approach to education and its commitment to advancing healthcare through rigorous clinical research. The university's diverse research programs are supported by a multidisciplinary team of experts dedicated to improving patient outcomes and public health. With a strong emphasis on evidence-based medicine, McMaster University actively engages in clinical trials that explore new therapies, interventions, and health technologies, fostering collaboration among researchers, healthcare professionals, and industry partners to translate findings into real-world applications.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hamilton, Ontario, Canada
Patients applied
Trial Officials
Lisa Carlesso, PhD
Principal Investigator
McMaster University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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