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Search / Trial NCT05745064

A Study of TL-925 as a Treatment for Dry Eye Disease

Launched by TELIOS PHARMA, INC. · Feb 22, 2023

Trial Information

Current as of May 28, 2025

Completed

Keywords

Tl 925 Phase Ii

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Individuals aged 18 years or older
  • A diagnosis of dry eye disease for at least 6 months
  • An unanesthetized Schirmer's test score (STS) of ≤ 10mm and ≥ 1mm in the study eye
  • A tear film break-up time (TFBUT) of ≤ 5 seconds in the study eye
  • A corneal fluorescein staining score of ≥ 2 in at least one region of the cornea
  • A sum corneal fluorescein staining score of ≥ 4 in the study eye
  • A total lissamine green conjunctival score of ≥ 2 in the study eye
  • Female subjects of childbearing potential and their male partners must both use a highly effective contraception method during the study.
  • Exclusion Criteria:
  • Any clinically significant slit lamp finding
  • Any ongoing ocular infection (bacterial, viral or fungal) or active ocular inflammation
  • Any keratorefractive surgery within the last 12 months
  • Any intraocular or extraocular surgery within 3 months

About Telios Pharma, Inc.

Telios Pharma, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for unmet medical needs in the field of dermatology and other specialty areas. With a commitment to advancing patient care, Telios leverages cutting-edge scientific research and a robust pipeline of product candidates aimed at addressing conditions characterized by inflammation and tissue repair. The company’s mission is to transform the standard of care through the discovery and development of novel treatments that enhance the quality of life for patients.

Locations

Andover, Massachusetts, United States

Colorado Springs, Colorado, United States

Newport Beach, California, United States

Indianapolis, Indiana, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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