Appendectomy During Pregnancy and Child Development
Launched by CLINICAL HOSPITAL CENTRE ZAGREB · Mar 5, 2023
Trial Information
Current as of May 27, 2025
Completed
Keywords
ClinConnect Summary
Maternal acute appendicitis (AA) is the most common emergent abdominal surgical condition during pregnancy. Brain development in a fetus is dynamic and complex, and therefore much more vulnerable to different agents. Gastrointestinal operations during pregnancy are performed in general anesthesia and anesthetic neurotoxicity in the developing brain, through the period from a fetus to a child, delivered inconsistent results.
Child development after AA or other intra-abdominal inflammatory/infective condition during pregnancy was not consistently reported or studied. In most reports, the len...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • all pregnant women operated for acute appendicitis (January 2006- December 2020)
- Exclusion Criteria:
- • pregnant women younger than 18
- • nonpregnant women
About Clinical Hospital Centre Zagreb
The Clinical Hospital Centre Zagreb is a leading medical institution in Croatia, dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the center prioritizes patient safety and ethical practices while exploring new therapies and treatment modalities across various medical disciplines. With a multidisciplinary team of healthcare professionals and state-of-the-art facilities, the Clinical Hospital Centre Zagreb is committed to contributing to the global medical community by enhancing the understanding of diseases and improving patient outcomes through rigorous scientific investigation.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Zagreb, , Croatia
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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