Effects of the Consumption of SEAweed Biomass Versus PROtein Isolates on Postprandial Satiety and Metabolism

Launched by SINGAPORE INSTITUTE OF FOOD AND BIOTECHNOLOGY INNOVATION · Mar 1, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how different types of seaweed protein affect feelings of fullness and metabolism after eating. Researchers want to see if using whole seaweed (like porphyra and chlorella) is better for health than just using the protein extracted from these seaweeds. They are particularly interested in how these foods influence blood sugar levels, availability of important nutrients, and hormones that control hunger.

To participate in this study, you need to be a male of Chinese ethnicity, aged between 21 to 50 years, with a healthy body weight (BMI between 18.5 and 25). You shouldn’t have diabetes, allergies to common foods, or follow strict diets like vegetarian or vegan. If you choose to join, you will need to follow specific dietary guidelines during the study days and might be asked to make some changes to your eating habits. This could be a great opportunity to help researchers understand more about how seaweed can be used as a sustainable protein source in our diets!

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Male
• • Chinese ethnicity
• • Aged 21 to 50 years
• • Able to give informed consent
• • Body Mass Index (BMI) of 18.5 to 25.0 kg/m2
• Exclusion Criteria:
• • Diabetic (HbA1C ≥ 6.5%)
• • Smoking
• • Having a dislike towards seaweed- or soy-based products
• • Having allergies or intolerances to any common food ingredients including seaweed, soy, eggs, seafood, fish, milk, peanuts, tree nuts, wheat, gluten, cereal, fruits, dairy products, meat, vegetables, sugar, sweeteners, natural food colourings or flavourings, etc.
• • Following special diets or having intentional dietary restrictions (e.g, vegetarians/vegans)
• • Not willing to adhere to diet modification as in the study protocol
• • Taking part in strenuous physical activities
• • Not willing to stop any strenuous activity during or within 24 hours of study days (for those actively participating in sports at the competitive and/or endurance levels)
• • Having glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
• • Having alcohol consumption on \> 4 days per week with ≥ 6 alcoholic drinks per week
• • Having sustained elevation of blood pressure (≥140/90 mm Hg)
• • Having previously undergone any gastrointestinal surgery or having history of gastrointestinal disorders
• • Having a history of heart, liver, kidney, blood disorders (e.g., thalassemia) or thyroid dysfunctions
• • Having history of tuberculosis, HIV, Hepatitis B or Hepatitis C infections
• • Having any prescription medication or any other alternative medicines or supplements which may interfere with study measurements in the opinion of the study investigators
• • Having donated blood within 4 weeks of study participation
• • Having poor veins or having history of severe vasovagal syncope (blackouts or fainting) from blood draws