Salivary LINC00657 as a Diagnostic Biomarker for Oral Squamous Cell Carcinoma
Launched by FAYOUM UNIVERSITY · Apr 19, 2023
Trial Information
Current as of May 09, 2025
Completed
Keywords
ClinConnect Summary
This study was designed to verify the role of salivary LINC00657 as a diagnostic marker in oral squamous cell carcinoma (OSCC) patients as compared to oral lichen planus (OLP) (as an example of oral potentially malignant lesions) and normal individuals, and to show its relation to miR-106a. A total of 36 participants were included, subdivided into 3 groups: Group I: 12 patients diagnosed with OSCC. Group II: 12 patients diagnosed with OLP. Group III: 12 systemically free individuals with no oral mucosal lesions. statistical analysis and ROC analysis were performed
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • group I : oral squamous cell carcinoma lesions (OSCC)
- • group II: oral lichen planus lesions (OLP)
- • group III: systemically healthy volunteers
- Exclusion Criteria:
- • oral lesions other than OSCC / OLP in group I and II
- • any oral lesion in group III
- • pregnant females
About Fayoum University
Fayoum University, a prominent higher education institution in Egypt, is dedicated to advancing medical research and enhancing healthcare outcomes through innovative clinical trials. With a commitment to academic excellence and community health improvement, the university leverages its diverse expertise and state-of-the-art facilities to conduct rigorous clinical studies. By fostering collaboration among researchers, healthcare professionals, and participants, Fayoum University aims to contribute valuable insights to the medical field and promote evidence-based practices that benefit society at large.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Fayoum, , Egypt
Patients applied
Trial Officials
Nayroz Tarrad, as. professor
Principal Investigator
faculty of dentistry, Fayoum university
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported