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Search / Trial NCT05906381

Dry Eye Symptom Mitigation by Oral Intake of Probiotics

Launched by CHUNG SHAN MEDICAL UNIVERSITY · Jun 14, 2023

Trial Information

Current as of May 15, 2025

Recruiting

Keywords

Probiotics Dry Eye Eye Sore Eye Strain

ClinConnect Summary

This clinical trial is looking at whether taking a daily capsule of probiotics can help relieve symptoms of dry eye. Dry eye can cause discomfort and vision problems, and this study aims to see if the probiotics can improve the health of the eyes by examining various factors, such as tear volume and quality. Participants in the trial will be adults aged 20 to 65 who have been diagnosed with dry eye, specifically those showing certain signs of the condition.

If you qualify for this study, you'll be asked to take one probiotics capsule each day for 35 days. During this time, the researchers will check your eye health before and after the trial to see if there are any improvements. To join, you need to meet specific criteria, such as having a certain level of tear production or eye discomfort. However, some individuals—like those with certain eye diseases, chronic health issues, or those in vulnerable situations—won’t be able to participate. This trial is currently recruiting participants, and it could be a promising opportunity for those struggling with dry eye symptoms.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • aged between 20 and 65 years
  • with Schirmer's test results less than 10 mm or Ocular Surface Disease Index more than 25
  • Exclusion Criteria:
  • evident ocular diseases such as cornea disease, cataract, vitreous degeneration, glaucoma, and retinopathy.
  • diabetes
  • hypertension
  • or other chronic diseases or belong to vulnerable groups(pregnancy woman, prisoner, ethical minorities, economic or educationally disadvantaged subjects, disabled individuals such as those at terminal stage of tumorigenesis, blindness, terminal ill individuals)

About Chung Shan Medical University

Chung Shan Medical University is a distinguished academic institution dedicated to advancing medical education, research, and healthcare services. As a clinical trial sponsor, the university leverages its expertise in medical sciences and innovative research methodologies to conduct rigorous and ethically sound clinical studies. With a commitment to enhancing patient care and contributing to the global body of medical knowledge, Chung Shan Medical University collaborates with healthcare professionals and research institutions to explore new therapeutic interventions and improve clinical outcomes. Through its comprehensive approach to research, the university plays a pivotal role in fostering advancements in medical science and public health.

Locations

Taichung, , Taiwan

Patients applied

0 patients applied

Trial Officials

David Pei-Cheng Lin

Principal Investigator

Chung Shan Medical University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported