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Search / Trial NCT05953896

Efficacy of HA Gel Injection Versus Multilayer (L-PRF) in the Interdental Papilla Reconstruction

Launched by AYA ELLEITHY · Jul 19, 2023

Trial Information

Current as of June 05, 2025

Completed

Keywords

Interdental Papilla Multilayer L Prf Hyaluronic Acid Gel

ClinConnect Summary

A total of 20 patients recruited from the outpatient clinic of Oral Medicine, Periodontology and Oral Diagnosis department, Faculty of Dentistry, Ain-Shams University and seeking treatment for black triangles for esthetic reason. Patients meeting the eligibility criteria are equally and randomly allocated in two different groups. group one Included 10 patients who received interdental papillary reconstruction using multiple layers of L-PRF. Group two Included 10 patients who received interdental papillary reconstruction using Hyaluronic acid gel injection. In the follow-up phase, patients w...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Both genders aged from 18-45 years.
  • 2. Systemically healthy patients.
  • 3. Patients with IDP loss class I or II of esthetic zone in upper and lower anterior and premolar teeth according to Nordland and Tarnow's classification (Class I: Presence of the tip of the papilla between interdental contact point and the interproximal CEJ)
  • 4. Presence of sufficient interdental alveolar bone (i.e. the vertical distance from the interdental contact point to the crest of the interdental bone is ≥ 5 mm) that was confirmed clinically by bone sounding.
  • 5. A band of keratinized tissue should be present around the test teeth ≥ 2 mm
  • 6. Periodontal phenotype of the area to be treated is ≥ 2 mm in thickness. Surgical reconstruction of IDP is influenced by gingival tissue phenotype, outcome of papilla reconstruction is better in cases with a thick gingival unit
  • 7. Patients with good oral hygiene and caring about esthetics and concerned to go through the management of "black triangles" by interdental papillae reconstruction in esthetic zone.
  • Exclusion criteria:
  • 1. Teeth with acute periapical pathosis.
  • 2. Patients with poor oral hygiene, incompliance to treatment and persistence of gingival inflammation after phase I therapy.
  • 3. Pregnant and lactating females.
  • 4. Patients having para-functional habits or local causes as, malocclusion, interdental spacing, rotation, inclination or crowding.
  • 5. Smokers, alcoholics or drug abusers.
  • 6. Vulnerable group of patients, orphans, handicapped, prisoners or mentally retarded patients.

About Aya Elleithy

Aya Elleithy is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes. With a focus on innovative therapies and cutting-edge technologies, the organization collaborates with leading healthcare professionals and institutions to design and conduct rigorous clinical studies. Aya Elleithy prioritizes ethical standards and regulatory compliance, ensuring that all trials are conducted with the utmost integrity and transparency. By fostering a culture of collaboration and scientific excellence, Aya Elleithy aims to contribute significantly to the development of new treatments and enhance the overall quality of care in the medical field.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Trial Officials

Aya Alleithy, teaching assistant

Principal Investigator

Teaching assistant at Department of Oral medicine, Periodontology, and Oral Diagnosis, Faculty of Dentistry, A

Hala Abu El-Ela, proffessor

Study Director

Professor of Oral Medicine, Periodontology and Oral Diagnosis , Faculty of Dentistry-Ain Shams University & Misr International university

Susan Sarhan, lecturer

Study Director

Lecturer of Oral Medicine and Periodontology and Oral diagnosis, Faculty of Dentistry, Ain Shams University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported