The Stool Microbiome of Treated and Untreated IBS (Irritable Bowel Syndrome) Patients

Launched by WEIZMANN INSTITUTE OF SCIENCE · Jul 23, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the gut bacteria and their effects on people with Irritable Bowel Syndrome (IBS), a common digestive disorder that affects many individuals worldwide. Researchers want to understand how changes in gut bacteria, along with what people eat, may contribute to IBS symptoms. They are particularly interested in the small molecules produced by gut bacteria and how these might impact gut health. The study will also look at the effectiveness of a specific diet called the low-FODMAP diet, which involves avoiding certain foods that can cause digestive discomfort.

To participate in this trial, individuals must be between the ages of 18 and 70 and cannot have taken antibiotics or probiotics recently, among other health-related criteria. Participants should not have certain chronic conditions, pregnancy, or psychiatric disorders. Those who join the study can expect to share information about their diet and gut health, and they will contribute to important research that could lead to better understanding and treatment of IBS. This trial is currently recruiting participants, and it aims to shed light on how diet and gut bacteria work together in managing IBS symptoms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male and Female
• • Age - 18-70
• Exclusion Criteria:
• • Consumption of antibiotics 2 months prior to the first day of the experiment.
• • Consumption of probiotic supplements 1 month prior to the first day of the experiment.
• • Type 1 or type 2 diabetes diagnosis.
• • Pregnancy, fertility treatments, breastfeeding 3 months prior to the first day of the study.
• • Chronic disease - to the discretion of the study doctor.
• • Cancer and recent anticancer treatment.
• • Psychiatric disorders - to the discretion of the study doctor.
• • IBD (inflammatory bowel diseases).
• • Alcohol or substance abuse.
• • BMI \> 35.

Trial Officials