Clinical Study of Lacrimal Drainage Obstruction Diseases Using Dacryoendoscopy
Launched by TIANJIN EYE HOSPITAL · Aug 13, 2023
Trial Information
Current as of June 13, 2025
Completed
Keywords
ClinConnect Summary
Lacrimal drainage obstruction can manifest as epiphora or recurrent infections with mucopurulent discharge and may even cause social embarrassment. Obstruction can occur at any level along the lacrimal drainage system: punctum, canaliculus, nasolacrimal duct, or nasal ostium. It is seen more often in females, especially in postmenopausal women. The etiopathogenesis of lacrimal passage obstruction appears to be multifactorial. Chronic inflammation has been suggested to be the most causal. Dacryocystorhinostomy (DCR) is a standard surgical procedure used to treat nasolacrimal duct obstruction...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • (1) confirmed diagnosis of nasolacrimal duct obstruction or stenosis, based on dacryoendoscopic examination with or without radiologic confirmation on dacryocystogram; (2) recurrent or persistent and symptomatic epiphora; (3) follow-up of longer than 6 months after removal of the silicone stent.
- Exclusion Criteria:
- • (1) congenital or traumatic lacrimal duct obstruction; (2) previous acute dacryocystitis; (3) facial nerve palsy; (4) lower eyelid or punctal malposition or laxity of sufficient severity to contribute to epiphora; (5) previous dacryocystorhinostomy; (6) incomplete medical records.
About Tianjin Eye Hospital
Tianjin Eye Hospital is a leading medical institution specializing in ophthalmology, dedicated to advancing eye health through innovative research and clinical excellence. As a prominent clinical trial sponsor, the hospital is committed to conducting rigorous studies that explore new treatments and therapies for a variety of eye-related conditions. With state-of-the-art facilities and a team of experienced professionals, Tianjin Eye Hospital fosters collaboration with researchers and healthcare providers to enhance patient care and contribute to the global understanding of ocular health. Its focus on patient-centered research ensures that clinical trials are designed to prioritize safety, efficacy, and the well-being of participants.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tianjin, Tianjin, China
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported