Local Delivery of Silk Fibroin and Chlorhexidine

Launched by KRISHNADEVARAYA COLLEGE OF DENTAL SCIENCES & HOSPITAL · Sep 16, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating the use of a special substance called silk fibroin as a way to deliver medication to treat periodontal pockets, which are spaces that can form in the gums due to gum disease. Researchers want to see how well silk fibroin works compared to a common treatment called chlorhexidine. This trial is in the early phase, and they are not yet recruiting participants.

To be eligible for this study, participants should be between 30 and 50 years old and have mild to moderate gum disease, specifically localized periodontal pockets. It's important that participants are willing to take part in the study. However, people with certain health conditions, those who have had recent dental treatment, pregnant or breastfeeding women, and those who have taken antibiotics in the past six months won't be able to join. Participants will have the opportunity to help researchers learn more about new treatments for gum disease, which could improve care for many patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patient with age between 30-50 years.
• • 2. Patients with stage I/ II with Grade A/ B periodontitis according to 2017 World workshop classification of periodontal disease will be considered.
• • 3. Patients with localized periodontal pockets.
• • 4. Patients willing to participate in the study.
• Exclusion Criteria:
• • 1. Patients with known systemic diseases.
• • 2. Non complaint patients.
• • 3. Patients who received any surgical or nonsurgical therapy 6 months before the start of the study.
• • 4. Pregnant or lactating females.
• • 5. Use of systemic antibiotics in the past 6 months.